MiSeq Software Updater

The MiSeq v3.0 software updater has been temporarily removed from the web. Contact Illumina Tech Support for more information.

For full installation instructions, see the installation notes included with the updater download package. The most recent update still uses Reference Genome v1.1.0.0 for MiSeq and there is no need to update the reference genome.

Note: The software updater can also be installed in the RUO drive of MiSeqDx instruments with dual boot configuration. If you are not sure if your instrument has dual boot configuration, contact Illumina Tech Support.


File Name
File Info
Date Posted
MiSeq Updater v2.6 ZIP(1 GB) 05/27/2016
MiSeq Software v2.6 Release Notes PDF(< 1 MB) 06/08/2016
MiSeq Updater v2.5.0.4 ZIP(508 MB) 09/22/2014
MiSeq Software v2.5 Release Notes PDF(< 1 MB) 09/23/2014
MiSeq Reporter v2.4 ZIP(342 MB) 03/24/2014
MiSeq Software v2.4 Release Notes PDF(< 1 MB) 05/01/2014
Reference Genome Updater v1.1 ZIP(8 GB) 10/15/2012