Before downloading Illumina software, you must first read and agree to the following EULA.
For NextSeq 1000/2000 DRAGEN workflow installers, refer to the NextSeq 1000/2000 downloads page.
Illumina discontinued support of the CentOS 7 operating system for all DRAGEN Servers on June 30, 2024. For information on upgrading DRAGEN servers to Oracle 8, refer to the DRAGEN secondary analysis Oracle 8 upgrade instructions available at https://knowledge.illumina.com.
| DRAGEN Release | Installers | DRAGEN Software Release Notes | User Guide | Date Posted | Readme |
|---|---|---|---|---|---|
| v4.4 | v4.4.4 Software Release Notes | v4.4 User Guide | May 6, 2025 | ||
| v4.3 | v4.3.13 Software Release Notes | v4.3 User Guide | DRAGEN v4.3 Readme | ||
| v4.3.6 Software Release Notes | |||||
| v4.2 | v4.2.9 Software Release Notes | v4.2 User Guide | DRAGEN v4.2 Readme | ||
| v4.2.7 Software Release Notes | |||||
| v4.2.4 Software Release Notes | |||||
| v4.1 | v4.1.23 Software Release Notes | v4.1 User Guide | DRAGEN v4.1 Readme | ||
| v4.1.7 Software Release Notes | |||||
| DRAGEN v4.1.5 Software Release Notes | |||||
| v4.0 | DRAGEN v4.0.5 Software Release Notes | v4.0 User Guide | DRAGEN v4.0 Readme | ||
| DRAGEN v4.0.3 Software Release Notes |
| DRAGEN Release | Application | Description | User Guide | Date Posted | Readme |
|---|---|---|---|---|---|
| v4.4 | Heme WGS analysis-Windows | Download utility to enable secondary analysis of Heme WGS samples. Generates SNVs, INDELs, CNAs, SVs, FLT3-ITD, and DUX4 variants | Heme WGS Analysis User Guide | May 9, 2025 | Readme |
| Heme WGS analysis-Unix | |||||
| Heme WGS analysis-Mac | |||||
| Solid WGS Tumor-Normal analysis-Windows | Download utility to enable secondary analysis of Solid WGS Tumor-Normal samples. Generates SNVs, INDELs, CNAs, SVs, TMB, MSI, HRD score, tumor purity, ploidy, and structural rearrangements. | Solid WGS Tumor-Normal User Guide | May 9, 2025 | Readme | |
| Solid WGS Tumor-Normal analysis-Unix | |||||
| Solid WGS Tumor-Normal analysis-Mac |
| DRAGEN Release | Installers | Date Posted | Software Release Notes | Date Posted | User Guide | Date Posted | EULA and Readme |
|---|---|---|---|---|---|---|---|
| v3.10.17 | May 8, 2024 | v3.10.17 Software Release Notes | May 9, 2024 | v3.10 User Guide | v3.10 Software EULA and Readme | ||
| v3.10.16 | May 6, 2024 | v3.10.16 Software Release Notes | Jan 16, 2024 | ||||
| 3.10.14 | May 6, 2024 | v3.10.14 Software Release Notes | May 6, 2024 |