HiSeq Analysis Software v2.1 requires CentOS 6 (or later) with the standard set of included libraries, which are indicated in the RPM installer. HiSeq Analysis Software also requires the R statistical package, which is not specified in the RPM. For R statistical package installation procedures and a complete list of dependencies, see the HiSeq Analysis Software v2.1 User Guide.
Proper function and performance of HiSeq Analysis Software v2.1 requires specific compute architecture. Required hardware is required from a range of suppliers and manufacturers.
Illumina recommends the following architecture for analyzing data from the HiSeq X Ten System. The recommendation does not include archival storage.