Thank you for visiting the customer support site for the Local Run Manager (LRM) Security Vulnerability correction. This is the software correction for the LRM security vulnerability of which customers were informed and a temporary security patch was provided in May 2022.
The following table lists the impacted instruments and the required actions for each instrument. Please note, all prior versions of control software which utilize LRM will no longer be available for distribution by Illumina once the software versions listed below are released.
Upon completion of the successful software upgrade, follow Illumina Cybersecurity best practices, including confirming that the firewall is enabled, and Universal Copy Service is running as a standard user.
| Instrument | Action | Release Date |
|---|---|---|
| iScan | None | N/A |
| NextSeq 1000 / NextSeq 2000 | None | N/A |
| NovaSeq 6000 | None | N/A |
| NovaSeq 6000Dx | None | N/A |
| NovaSeq X | None | N/A |
| NextSeq 500 / NextSeq 550 | Illumina Field Support to update Nextseq Control Software v4.2 and available LRM modules. | May 31, 2023 |
| NextSeq 550Dx | Update NextSeq Dx Control when released | Q3 2023 |
| MiSeq RUO | Update MiSeq Control Software when released | Q4 2023 |
| MiSeq Dx | Update MiSeq Dx Control Software when released | Q4 2023 |
| iSeq 100 | Update iSeq Control Software when released | Q1 2024 |
| MiniSeq | Update MiniSeq Control Software when released | Q1 2024 |
Software Installation requires onsite Illumina support. An Illumina Field Representative will contact you to schedule an onsite visit to install NextSeq Control Software v4.2.0.
Customer release notes are available here.
| NextSeq 550 Module Description | Compatible Version with NextSeq Control Software v4.2 | Availability |
|---|---|---|
| DNA Amplicon | v3.0.1.1 | Modules available on the Illumina Support Site. |
| DNA Enrichment | v3.0.0.23 | |
| GenerateFASTQ | v3.0.1.49 | |
| Resequencing | v3.0.1.13 | |
| 16s Metagenomics |
v2.0.0.5 | |
| Library QC | v2.1.0.18 | |
| RNA Amplicon | v3.0.0.26 | |
| PCR Amplicon | v2.0.0.3 | |
| Assembly | v2.0.1.2 | |
| VeriSeq NIPT | v1.0.4.3 | Planned for Q3 2023 |
| TruSight Oncology 500 | v2.3 | Planned for Q3 2023 |
| Small RNA | N/A | Planned for Q4 2023 |
| RNA Fusion | N/A | Planned for Q4 2023 |
| Amplicon DS | N/A | Planned for Q4 2023 |
Local Run Manager Off-Instrument v3.0 installer and release notes.
Local Run Manager Off-Instrument v2.0 installer and release notes.
Local Run Manager Off-Instrument installer and release notes.
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